phytochemical investigation of vinca minor cultivated in iran

نویسندگان

behnaz farahanikia department of pharmacognosy and medicinal plants research center, faculty of pharmacy, tehran university of medical sciences, tehran, iran.

tahmineh akbarzadeh department of medicinal chemistry, faculty of pharmacy, tehran university of medical sciences, tehran, iran.

akbar jahangirzadeh department of pharmacognosy and medicinal plants research center, faculty of pharmacy, tehran university of medical sciences, tehran, iran.

narguess yassa department of pharmacognosy and medicinal plants research center, faculty of pharmacy, tehran university of medical sciences, tehran, iran.

چکیده

lesser periwinkle (vinca minor l.), a member of apocynaceae, is not only an ornamental plant with lilac-blue flowers, but also a medical plant producing an important alkaloid, vincamine, found in the leaves which shows a pronounced cerebrovasodilatory and neuroprotective activity. this plant is native to northern spain, western france, central and southern europe, and caucasus. it has been recently cultivated for pharmaceutical purposes by zardband botanical garden in iran. since the quality of herb material and alkaloid concentration is greatly influenced by environmental conditions, in this study, we report the isolation and identification of major alkaloids along with the quantification of vincamine as the pharmacologically most important component. alkaloids from the aerial parts of v. minor were isolated and purified using different chromatographic methods. the structures of these alkaloids were determined on the basis of their physical and spectroscopic data. the concentration of vincamine was determined by high performance liquid chromatography using tracer excel 120 ods a c18 column. five indole alkaloids including vincaminorine, vincaminoreine, minovine, minovincine, and vincamine (figure 1) were isolated from the aerial parts of v. minor. vincamine was found to be the dominant alkaloid in this plant with the content of 0.057% of the dried plant mass. this plant may be used as a natural source for pharmaceutical purposes in iran, due to the presence of biologically active alkaloids especially vincamine as the major alkaloid in lesser periwinkle cultivated.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Phytochemical Investigation of Vinca minor Cultivated in Iran

Lesser Periwinkle (Vinca minor L.), a member of Apocynaceae, is not only an ornamental plant with lilac-blue flowers, but also a medical plant producing an important alkaloid, vincamine, found in the leaves which shows a pronounced cerebrovasodilatory and neuroprotective activity. This plant is native to northern Spain, western France, central and southern Europe, and Caucasus. It has been rece...

متن کامل

Phytochemical Investigation of Vinca Minor Cultivated in Iran

Lesser Periwinkle (Vinca minor L.), a member of Apocynaceae, is not only an ornamental plant with lilac-blue flowers, but also a medical plant producing an important alkaloid, vincamine, found in the leaves which shows a pronounced cerebrovasodilatory and neuroprotective activity. This plant is native to northern Spain, western France, central and southern Europe, and Caucasus. It has been rece...

متن کامل

Phytochemical Investigation of Vinca Minor Cultivated in Iran

Lesser Periwinkle (Vinca minor L.), a member of Apocynaceae, is not only an ornamental plant with lilac-blue flowers, but also a medical plant producing an important alkaloid, vincamine, found in the leaves which shows a pronounced cerebrovasodilatory and neuroprotective activity. This plant is native to northern Spain, western France, central and southern Europe, and Caucasus. It has been rece...

متن کامل

ANTIMICROBIAL ACTIVITY AND SOME PHYTOCHEMICAL ANALYSIS OF TWO EXTRACTS Vinca minor L

This study investigated the antimicrobial activity as well as some phytochemical analysis of ethanol and diethyl ether extracts from plant species Vinca minor L. In vitro antimicrobial activity of extracts was studied on 20 strains of microorganisms (16 bacteria and four yeasts). Testing was performed by microdilution method and minimum inhibitory concentration (MIC) and minimum microbicidal co...

متن کامل

Phytochemical and biological Investigation of Clivia nobilis flowers Cultivated in Egypt

Amaryllidaceae is a well-known family for its high alkaloidal content. These alkaloids comprise a unique group of bases that have been found to occur in this family. The Amaryllidaceae alkaloids represent a large and still expanding group of isoquinoline alkaloids, the majority of which are not known to occur in any other family of plants This article reports on the phytochemical investigation ...

متن کامل

Phytochemical and biological Investigation of Clivia nobilis flowers Cultivated in Egypt

Amaryllidaceae is a well-known family for its high alkaloidal content. These alkaloids comprise a unique group of bases that have been found to occur in this family. The Amaryllidaceae alkaloids represent a large and still expanding group of isoquinoline alkaloids, the majority of which are not known to occur in any other family of plants This article reports on the phytochemical investigation ...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
iranian journal of pharmaceutical research

جلد ۲۰۱۱، شماره ۴، صفحات ۷۷۷-۷۸۵

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023